The Large Lips are one of the eight items (nine, if the Smile counts) that can be purchased from the Item Shop in the Game Boy Advance game Wario Land 4. The Large Lips can be bought off Mr. Game & Watch, the shop keeper, for 10 Frog Medals (depending on the game mode, it could cost more). All Items from the Item Shop are there to assist Wario in defeating a challenging Boss by doing pre-damage at the battle's beggining.
Effect
When purchased, Mr. Game & Watch will follow Wario to the Boss Room. His head will then transform and be replaced with a large pair of lips, which will then kiss the Boss, causing 7HP worth of damage. Mr Game and Watch will then transform back into his old self and then leave the room, leaving Wario to fight a weakened Boss.