Item Boxes are boxes in the Mario Kart series. Item Boxes look like ? Blocks but are transparent and often blue, and in more recent games they have a iridescent checker board pattern. When a character passes through them, they will get a random/semi-random item. These blocks also appear in Mario Tennis and Mario Power Tennis. They have appeared in all the Mario Kart games, except Super Mario Kart where they used ? Panels.

In the Mission Mode of Mario Kart DS, the player's task occasionally is to destroy a certain amount of Item Boxes (which often contain Mushrooms to give the driver a boost).

There are also Fake Item Boxes and Double Item Boxes.

File:MKAGP2itemboxes.jpg
In Mario Kart Arcade GP 2, item boxes have an hexagonal design.